The effect of two novel cholesterol-lowering agents, disodium ascorbyl phytostanol phosphate on the expression and activity of P-glycoprotein within Caco-2 cells

Background Many drugs are substrates for P-glycoprotein (P-gp) and interactions involving P-gp may be relevant to clinical practice. Co-administration with P-gp inhibitors or inducers changes the absorption profile as well as the risk for drug toxicity, therefore it is important to evaluate possible...

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Veröffentlicht in:	Lipids in health and disease 2014-10, Vol.13
Hauptverfasser:	Sachs-Barrable, Kristina, Darlington, Jerald W, Wasan, Kishor M
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Cardiovascular agents Genes Physiological aspects
Online-Zugang:	Volltext
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