Intermittent hemodialysis in dogs with chronic kidney disease stage III/Hemodialise intermitente em caes com doenca renal cronica III

Intermittent hemodialysis (IHD) is a form of renal replacement that is used in veterinary medicine for cases involving drug removal, electrolyte imbalance, acute kidney injury, and chronic kidney disease (CKD). The aim of the present study was to verify the efficacy of IHD in dogs with CKD staged at grade III and to evaluate the effect of IHD on quality of life. Twelve dogs with CKD at stage III met the inclusion criteria and were divided equally into two groups. The control group (n=6) received only clinical treatment and intravenous fluid therapy, and the hemodialysis group (n=6) received clinical and IHD treatments. Blood samples were collected before and after treatments in both groups. We evaluated complications and clinical parameters of IHD every 30 minutes. Hemodialysis decreased serum urea, creatinine, and phosphorus. Despite the evident removal of nitrogen compounds, dialysis treatment did not increase survival time in these patients. The results of this study do not support the early use of dialysis in dogs with chronic kidney disease stage III. Key words: dialysis, CKD, kidney, nephrology, dog. A Hemodialise Intermitente (HDI) e uma modalidade de substituicao renal, utilizada na veterinaria nos casos de remocao de drogas, disturbios hidroeletrolitico, lesao renal aguda e doenca renal cronica (DRC). O objetivo do presente estudo foi estudar o efeito da hemodialise intermitente em caes com DRC estadeados no grau III, visando avaliar a qualidade de vida. Foram selecionados 12 caes com DRC no estadio IIIpelos criterios de inclusao, apos foram divididos em Grupo Controle (n=6), onde foi preconizado apenas tratamento clinico e fluidoterapia, e Grupo hemodialise (n=6), que alem do tratamento clinico, utilizou-se a hemodialise intermitente. A colheita de sangue para avaliacao laboratorial foi realizada antes e apos a fluidoterapia de ambos os grupos. Foram avaliados as intercorrencias e os parametros clinicos durante a HDI a cada 30 minutos. A instituicao do tratamento dialitico promoveu uma eficaz diminuicao das concentracoes sericas de ureia, creatinina e fosforo de modo mais precoce. Apesar da evidente remocao dos compostos nitrogenados, o tratamento dialitico nao aumentou a sobrevida destes pacientes, nao justificando o emprego desta tecnica de forma precoce em caes com doenca renal cronica no estadio III. Palavras-chave: dialise, DRC, rim, nefrologia, cao.