Association between oral lichen planus and hepatitis C: retrospective study and case report/Associacao entre liquen plano oral e hepatite C: estudo retrospectivo e relato de caso
Oral Lichen Planus (OLP), a chronic inflammatory disease of unknown etiology, which affects the skin and/or mucosal tissues, is an autoimmune disease (pathology) of special interest to dentists due to its oral manifestations and its possible association with Hepatitis C virus (HCV). Although a possi...
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Veröffentlicht in: | Acta scientiarum. Health sciences 2017-01, Vol.39 (1), p.107 |
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Format: | Artikel |
Sprache: | spa |
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Zusammenfassung: | Oral Lichen Planus (OLP), a chronic inflammatory disease of unknown etiology, which affects the skin and/or mucosal tissues, is an autoimmune disease (pathology) of special interest to dentists due to its oral manifestations and its possible association with Hepatitis C virus (HCV). Although a possible association has been extensively discussed in the literature, the results have been controversial. So that the relationship between Oral Lichen Planus (OLP) and infection by HCV (OLP-HCV) may be investigated, current study conducted an epidemiological survey of all OLP cases diagnosed in two reference projects, with regard to diagnosis, treatment and epidemiology of oral lesions in Maringa, Parana, Brazil. In addition, the clinical case of a patient with HCV and the clinical manifestation of severe OLP will be provided. A total of 3,488 clinical records of biopsies performed between 1994 and 2014 and 85 cases of OLP were selected for the present study. The reticular type of OLP showed significant prevalence but only 2.3% of OLP cases revealed any association with HCV. Palavras-chave: liquen plano, hepatite C, epidemiologia. Liquen Plano (LP) e uma doenca inflamatoria cronica de etiologia desconhecida, que acomete pele e/ou mucosas. Esta doenca autoimune e de especial interesse para o cirurgiao-dentista pelo fato de apresentar manifestacoes bucais e pode estar associado ao virus da hepatite C (VHC). Esta possivel associacao tem sido muito discutida na literatura, apresentando resultados controversos. Com o intuito de investigar a relacao entre o Liquen Plano Oral (LPO) e a infeccao pelo VHC (LPO-VHC), o presente trabalho objetivou conduzir um levantamento de todos os casos de LPO diagnosticados em dois projetos de referencia quanto a diagnostico, tratamento e epidemiologia de lesoes bucais na cidade de Maringa, Parana, Brasil. Adicionalmente, um caso clinico de um paciente portador do VHC com manifestacao clinica severa de liquen plano sera apresentado. Foram selecionados para o presente estudo um total de 3.488 prontuarios de biopsias realizadas entre os anos de 1994 e 2014 e 85 casos de LPO. O LPO do tipo reticular apresentou prevalencia estatisticamente significante e apenas 2.3% dos casos de LPO apresentaram associacao com o VHC. Keywords: lichen planus, hepatitis C, epidemiology. |
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ISSN: | 1679-9291 |
DOI: | 10.4025/actascihealthsci.v39i1.27018 |