Efficacy of antimicrobial and antioxidant activity of Solanum xantocarpum whole plant hot aqueous extracts

Present study was carried out to test the efficacy of hot whole plant aqueous extract (HAE) of Solanum xanthocarpum Schrad and Wendl fam. Solanaceae against some gram positive and gram negative bacteria and its antioxidant activity. Hot whole plant aqueous extract (HAE) showed the significant(p>.01) antibacterial activity against the Bacillus subtilis, Staphylococus aureus, Escherichia coli, Pseudomonos aeruginosa but no antifungal activity against Candida albicans. Tetracyclin and fluconazole was used as the standard antibiotic for bacteria and fungi. MIC of Hot whole plant aqueous extract (HAE) was calculated , MIC of P.aeruginosa found to be low 0.039mg/ml, .156 mg/ ml for Staphylococus aureus and Bacillus subtilis, no MIC was to found against Escherichia coli and fungi Candida albicans. 2,2-diphenylhydrazyl free radical scavenging assay was use to determine the invitro antioxidant activity of Hot whole plant aqueous extract (HAE) of Solanum xanthocarpum for concentration 0.25mg/ml, 0.5mg/ml, 1.0mg/ml and 2mg/ml as compared to standard ascorbic acid and butylated hydroxyl toluene, resultshow the significant (p>0.1) antioxidant activity. Keywords: Solanum xantocarpum, whole plant aqueous, antimicrobial.