Synthesis and Immunotropic Activity of Quinazolin-4(3H)-One Carbonyl Derivatives

Synthesis and Immunotropic Activity of Quinazolin-4(3H)-One Carbonyl Derivatives

Novel benzannelated pyrimidines, i.e., quinazolin-4(3 H )-one derivatives, were synthesized and studied experimentally for possible immunotropic properties. Immunocorrection properties were observed for some substances (VMA-13, Nos. 01-04) with respect to immunosuppression caused by cyclophosphamide...

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Veröffentlicht in:Pharmaceutical chemistry journal 2016-09, Vol.50 (6), p.362-364
Hauptverfasser: Samotrueva, M. A., Tsibizova, A. A., Ozerov, A. A., Luzhnova, S. A., Glukhova, E. G., Tyurenkov, I. N.
Format: Artikel
Sprache:eng
Schlagworte:
Cyclophosphamide
Medicine
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
Pyrimidines
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Zusammenfassung:Novel benzannelated pyrimidines, i.e., quinazolin-4(3 H )-one derivatives, were synthesized and studied experimentally for possible immunotropic properties. Immunocorrection properties were observed for some substances (VMA-13, Nos. 01-04) with respect to immunosuppression caused by cyclophosphamide.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-016-1452-8