An incidental finding of thymic carcinoma during elective coronary artery bypass grafting/Slucajan nalaz karcinoma timusa tokom elektivne hirurske revaskularizacije miokarda

Introduction. Thymoma is a rare malignant tumor of the anterior mediastinum. Thymic squamous cell carcinoma has been recognized as an aggressive form of thymoma with different behavior. It is associated with paraneoplastic syndromes, variety of clinical presentations, different way of treatment and...

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Veröffentlicht in:Medicinski pregled 2016-05, p.167
Hauptverfasser: Jonjev, Zivojin S, Pavlovic, Milorad, Ilic, Bojan, Samardzija, Golub
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Sprache:eng
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Zusammenfassung:Introduction. Thymoma is a rare malignant tumor of the anterior mediastinum. Thymic squamous cell carcinoma has been recognized as an aggressive form of thymoma with different behavior. It is associated with paraneoplastic syndromes, variety of clinical presentations, different way of treatment and complex prognosis. Improved imaging techniques show that an early diagnosis of thymoma is possible, which makes thymoma a potentially dangerous but preventable disease. Case Report. In this report, we describe the clinical and histological findings of a patient with incidental finding of squamous cell thymic carcinoma presented during elective coronary artery bypass grafting surgery. Key words: Thymoma; Mediastinal Neoplasms; Elective Surgical Procedures; Myocardial Revascularization; Coronary Artery Bypass; Thymectomy; Immunohistochemistry; Carcinoma, Squamous Cell; Early Diagnosis; Morphological and Microscopic Findings Uvod. Timomi su retki maligni tumori prednjeg medijastinuma. Skvamocelularni karcinom timusa tretira se kao agresivna forma timoma sa znacajnom patoloskom nepredvidljivoscu. U cestoj je korelaciji sa paraneoplastickim sindromom, varijabilne je klinicke prezentacije, zahteva kompleksno lecenje koje prati nepredvidiva prognoza. Savremene dijagnosticke tehnike ukazuju na to da je rana dijagnoza timoma moguca. Na taj nacin povecava se verovatnoca za uspesnijim lecenjem timoma, kao potencijalno smrtonosnog oboljenja. Prikaz slucaja. U ovom prikazu opisana je klinicka slika, patohistoloski i imunohistohemijski nalaz skvamocelularnog karcinoma timusa koji je slucajno identifikovan kod pacijenta tokom elektivne hirurske revaskularizacije miokarda. Kljucne reci: karcinom timusa; karcinomi medijastinuma; elektivne hirurske procedure; miokardijalna revaskularizacija; bajpas koronarnih arterija; timektomija; imunohistohemija; skvamozni karcinom; rana dijagnoza; morfoloski i mikroskopski nalazi
ISSN:0025-8105
DOI:10.2298/MPNS1606167J