Content of HLA-[G.sup.+] T cells in the peripheral blood from healthy women and breast cancer patients
The number of [CD3.sup.+][CD56.sup.-]HLA-[G.sup.+] cells in the peripheral blood of breast cancer patients was shown to increase by 2 times. Our results and published data suggest that the increase in the relative content of [CD3.sup.+][CD56.sup.-]HLA-[G.sup.+] cells in the circulating blood in brea...
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Veröffentlicht in: | Bulletin of experimental biology and medicine 2015-09, p.649 |
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container_title | Bulletin of experimental biology and medicine |
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creator | Ostapchuk, E.O Perfileva, Yu. V Talaeva, Sh. Zh Omarbaeva, N.A Belyaev, N.N |
description | The number of [CD3.sup.+][CD56.sup.-]HLA-[G.sup.+] cells in the peripheral blood of breast cancer patients was shown to increase by 2 times. Our results and published data suggest that the increase in the relative content of [CD3.sup.+][CD56.sup.-]HLA-[G.sup.+] cells in the circulating blood in breast cancer contributes to tumor development due to suppression of antitumor immunity. Key Words: regulatory T cells; HLA-G; interleukin-10; TGFβ |
doi_str_mv | 10.1007/s10517-015-3038-y |
format | Article |
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Our results and published data suggest that the increase in the relative content of [CD3.sup.+][CD56.sup.-]HLA-[G.sup.+] cells in the circulating blood in breast cancer contributes to tumor development due to suppression of antitumor immunity. Key Words: regulatory T cells; HLA-G; interleukin-10; TGFβ</abstract><pub>Springer</pub><doi>10.1007/s10517-015-3038-y</doi></addata></record> |
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subjects | Breast cancer Care and treatment Health aspects Histocompatibility antigens HLA histocompatibility antigens T cells Transforming growth factors Tumor antigens Women |
title | Content of HLA-[G.sup.+] T cells in the peripheral blood from healthy women and breast cancer patients |
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