Lipid peroxidation in dogs naturally infected with Babesia canis canis/Lipidna peroksidacija u pasa prirodno zarazenih vrstom Babesia canis canis

The possible role of oxidative stress in the pathogenesis of infections caused by parasites has been an active area of research in recent years. The aim of this study was to assess changes in activity concentrations of malondialdehyde (MDA), a commonly used biomarker for assessing lipid peroxidation, in dogs infected with Babesia canis canis, after therapy with imidocarb dipropionate, and to compare them with MDA concentrations prior to treatment and to healthy controls. The study was conducted on a sample of 30 dogs suffering from babesiosis and 25 healthy dogs (control group). Blood was taken before treatment, on the first day (all dogs) and on the second, third, and seventh days of the research (affected dogs and ten healthy dogs). Application of imidocarb diproprionate in ten healthy dogs did not affect the values of MDA, so in our study all healthy dogs were used as controls. On the first day of the research the MDA concentrations were significantly increased in dogs with babesiosis (P