Mesenchymal hamartoma of the liver in adults--case report/Mezenhimalni hamartom jetre u adultnom dobu--prikazslucaja

Introduction. Mesenchymal hamartoma of the liver is a benign lesion presenting as an enlarging abdominal mass in children less than 2 years of age. Fewer than 5% cases are present in individuals over 5 years of age, and this lesion is extremely rare in adults. It may affect the left or the right lobe of liver as a cystic or solid mass or both components may be present. The pathogenesis remains incompletely understood, but these lesions have generally been considered to represent a development abnormality in the bile duct plate formation. Case Report. In this report, we present a case of a 44-year-old man who was surgically treated at the Department of Abdominal, Endocrine and Transplantation Surgery of the Clinical Center of Vojvodina due to cystic lesion in the liver segment IV that had been verified by computed tomography imaging diagnostics. The patient was sent from a smaller health center with the diagnosis of echinococcosis. After the adequate preparation of the patient, surgical excision of the liver cystic lesion was done. Once a thorough histological examination had been performed, the diagnosis of mesenchymal hamartoma was made. Conclusion. Mesenchymal hamartoma of the liver is a benign tumor resulting from abnormal, intra-uterine development of bile ducts and has a delayed clinical manifestation, thus this lesion appears to be related to the processes of maturation. It is potentially premalignant lesion presenting as a solid and/or cystic neoplasm. Symptoms, laboratory results and radiographic imaging are nonspecific and inconclusive, so surgical excision of the whole lesion is the imperative for the definitive diagnosis. Key words: Liver Neoplasms; Hamartoma; Adult; Diagnosis; Tomography, X-Ray Computed; Hepatectomy Uvod. Mezenhimalni hamartom jetre je benigni tumor koji se manifestuje kao rastuca masa u abdomenu obicno kod dece uzrasta do 2 godine. U manje od 5% slucajeva je dijagnostikovan kod uzrasta starijeg od 5 godina, dok je u odraslom dobu izuzetno redak. Moze zahvatati levi ili desni rezanj jetre, a javlja se kao solidni ili cisticni oblik, ili kombinacija ove dve forme. Prikaz slucaja. U radu je prikazan slucaj pacijenta starosti 44 godine koji je hirurski lecen na Klinici za abdominalnu, endokrinu i transplatacionu hirurgiju Klinickog centra Vojvodine zbog cisticne promene u IV segmentu jetre koja je verifikovana kompjuterizovanom tomografijom. Pacijent je poslat iz zdravstvenog centra iz unutrasnjosti sa dijagnozom ehinokokne ciste.