Synthesis and Anti-Inflammatory Activity of Ibuprofen Esters

Synthesis and Anti-Inflammatory Activity of Ibuprofen Esters

The anti-inflammatory activities of new ibuprofen esters with alcohol residues of different lengths were studied. These compounds were found to have anti-inflammatory and antiedema activities comparable to and in some cases greater than those of equimolar quantities of ibuprofen.

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Veröffentlicht in:Pharmaceutical chemistry journal 2014-08, Vol.48 (5), p.313-316
Hauptverfasser: Kravchenko, I. A., Kireva, M. V., Alekseeva, E. A.
Format: Artikel
Sprache:eng
Schlagworte:
Carrageenin
Esters
Ibuprofen
Medicine
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
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Zusammenfassung:The anti-inflammatory activities of new ibuprofen esters with alcohol residues of different lengths were studied. These compounds were found to have anti-inflammatory and antiedema activities comparable to and in some cases greater than those of equimolar quantities of ibuprofen.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-014-1101-z