Phenolic Acids and Antioxidant Activities of Danshen Injection

Phenolic Acids and Antioxidant Activities of Danshen Injection

A chemical study on the constituents of Danshen injection (lyophilized powder) led to the isolation of 15 compounds, including 13 phenolic acids, (R)-salvianolic acid G methyl ester (1), (R)-salvianolic acid G (2), tournefolic acid B (3), isosalvianolic acid C methyl ester (4), rosmarinic acid (5),...

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Veröffentlicht in:Chemistry of natural compounds 2014-03, Vol.50 (1), p.83-87
Hauptverfasser: Liu, Jing, Li, Wenjie, Jiang, Shoujun, Guo, Ying, Wang, Gangli, Lin, Ruichao
Format: Artikel
Sprache:eng
Schlagworte:
antioxidant activity
Antioxidants
freeze drying
hydroxymethylfurfural
Medicine
Organic Chemistry
Pharmacy
phenolic acids
Plant Sciences
rosmarinic acid
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Zusammenfassung:A chemical study on the constituents of Danshen injection (lyophilized powder) led to the isolation of 15 compounds, including 13 phenolic acids, (R)-salvianolic acid G methyl ester (1), (R)-salvianolic acid G (2), tournefolic acid B (3), isosalvianolic acid C methyl ester (4), rosmarinic acid (5), and 8 simple phenolics (6–13), together with 5-hydroxymethyl-2-furaldehyde (14) and 5-oxopyrrolidine-2-carboxylic acid (15). Among them, compound 1 was new, and 10 compounds showed potent antioxidant activities by in vitro DPPH· and ABTS ·⁺ scavenging methods with microplate assays.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-014-0872-5