Synthesis of Betulin Derivatives: N’{N-[3-OXO-20(29)-Lupen-28-OYL]-9-Aminononanoyl}3-Amino-3-Phenylpropionic Acid

Synthesis of Betulin Derivatives: N’{N-[3-OXO-20(29)-Lupen-28-OYL]-9-Aminononanoyl}3-Amino-3-Phenylpropionic Acid

A method for synthesizing N ’-{ N -[3-oxo-20(29)-lupen-28-oyl]-9-aminononanoyl}-3-amino-3-phenylpropionic acid, a compound that exhibited immunostimulating and antiviral activities, by adding the methyl ester of N -(9-aminononanoyl)-3-amino-3-phenylpropionic acid to betulonic acid was described.

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Veröffentlicht in:Pharmaceutical chemistry journal 2012-11, Vol.46 (8), p.473-477
Hauptverfasser: Sysolyatin, S. V., Surmachev, V. N., Malykhin, V. V., Kalashnikov, A. I., Surmacheva, I. A., Sonina, E. G., Dubkov, A. S., Tolstikov, G. A., Shul’ts, E. E., Salakhutdinov, N. F., Dzhemilev, U. M.
Format: Artikel
Sprache:eng
Schlagworte:
Antiviral agents
Medicine
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
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Zusammenfassung:A method for synthesizing N ’-{ N -[3-oxo-20(29)-lupen-28-oyl]-9-aminononanoyl}-3-amino-3-phenylpropionic acid, a compound that exhibited immunostimulating and antiviral activities, by adding the methyl ester of N -(9-aminononanoyl)-3-amino-3-phenylpropionic acid to betulonic acid was described.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-012-0828-7