Synthesis and pharmacological properties of alkylammonium salts of N,N′-malonyl-bis-p-aminobenzoic acid
A series of ammonium salts of N,N′-malonyl-bis-p-aminobenzoic acid with some alkylamines have been obtained. It is established that these compounds possess hypotensive, antiarrhythmic, and anticoagulative activities depending on the structure of the alkylamine constituents.
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Veröffentlicht in: | Pharmaceutical chemistry journal 2010-12, Vol.44 (9), p.469-471 |
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Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | A series of ammonium salts of N,N′-malonyl-bis-p-aminobenzoic acid with some alkylamines have been obtained. It is established that these compounds possess hypotensive, antiarrhythmic, and anticoagulative activities depending on the structure of the alkylamine constituents. |
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ISSN: | 0091-150X 1573-9031 |
DOI: | 10.1007/s11094-010-0493-7 |