Formation of ultrathin protective films for ophthalmological use from aqueous solutions of polymers and taurine

Aqueous dextran solutions, polyhexamethyleneguanidine hydrochloride and Sovidone and their mixtures with taurine were used to form stable ultrathin protective films for ophthalmological use. Addition of taurine to dextran and polyhexamethyleneguanidine solutions induced an association between polymer macromolecules in the two-dimensional film and a decrease in the surface activity of the solution. Addition of taurine to Sovidone solutions altered the conformation of macromolecular globules and increased the surface activity of the solution. Use of these solutions as the bases for eye drops did not harm the lipid layer of the tear film, and that rapidly formed polymer films could successfully be replaced by natural lipids via natural processes during recovery of the functions of the tear glands.