Synthesis and antibacterial activity of betulonic acid amides with piperazine derivatives
New betulonic acid amides with piperazine derivatives were synthesized by the acid-chloride method and characterized using spectral data. It was shown that synthesized compounds 2 – 7 exhibited varied antibacterial activity. The most active of them was betulonic acid amide of 1-(3,4-dichlorophenyl)p...
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| Veröffentlicht in: | Chemistry of natural compounds 2011-11, Vol.47 (5), p.759-763 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | New betulonic acid amides with piperazine derivatives were synthesized by the acid-chloride method and characterized using spectral data. It was shown that synthesized compounds
2
–
7
exhibited varied antibacterial activity. The most active of them was betulonic acid amide of 1-(3,4-dichlorophenyl)piperazine (
3
) and 1-(4-trifluoromethylphenyl)piperazine (
7
). |
|---|---|
| ISSN: | 0009-3130 1573-8388 |
| DOI: | 10.1007/s10600-011-0051-x |