4-hydroxy-2-quinolones. 176. 4-R-2-oxo-1,2-dihydroquinoline-3-carboxylic acids. synthesis, physicochemical and biological properties
We have carried out the synthesis and a comparative analysis of the acidic properties of a large group of 4-R-2-oxo-1,2-dihydroquinoline-3-carboxylic acids. Features of the recorded NMR spectra of these compounds are discussed together with their analgesic properties.
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| Veröffentlicht in: | Chemistry of heterocyclic compounds (New York, N.Y. 1965) N.Y. 1965), 2010-09, Vol.46 (5), p.559-568 |
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| container_title | Chemistry of heterocyclic compounds (New York, N.Y. 1965) |
| container_volume | 46 |
| creator | Ukrainets, I. V Davidenko, A. A Mospanova, E. V Sidorenko, L. V Svechnikova, E. N |
| description | We have carried out the synthesis and a comparative analysis of the acidic properties of a large group of 4-R-2-oxo-1,2-dihydroquinoline-3-carboxylic acids. Features of the recorded NMR spectra of these compounds are discussed together with their analgesic properties. |
| doi_str_mv | 10.1007/s10593-010-0546-6 |
| format | Article |
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| ispartof | Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2010-09, Vol.46 (5), p.559-568 |
| issn | 0009-3122 1573-8353 |
| language | eng |
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| source | SpringerNature Journals |
| subjects | 4-R-2-oxo-1,2-dihydroquinoline-3-carboxylic acids analgesic effect Analgesics Chemistry Chemistry and Materials Science Esters Hydrolysis Organic acids Organic Chemistry Pharmacy pKa |
| title | 4-hydroxy-2-quinolones. 176. 4-R-2-oxo-1,2-dihydroquinoline-3-carboxylic acids. synthesis, physicochemical and biological properties |
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