Synthesis of Calcium Glycinate and the Effects of Its Oral Administration on Biochemical Measures of Bone Metabolism in Mice and Rats
The complex Ca(Gly) 2 was synthesized and the chemical composition and structure of this chelate were studied. The possibility of using this calcium glycinate complex as a regulator of bone tissue metabolism was studied in development of experimental osteoporosis in mice and during healing of rat ti...
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| Veröffentlicht in: | Pharmaceutical chemistry journal 2013-06, Vol.47 (3), p.146-150 |
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| container_title | Pharmaceutical chemistry journal |
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| creator | Luneva, S. N. Nakoskin, A. N. Vaganova, L. A. |
| description | The complex Ca(Gly)
2
was synthesized and the chemical composition and structure of this chelate were studied. The possibility of using this calcium glycinate complex as a regulator of bone tissue metabolism was studied in development of experimental osteoporosis in mice and during healing of rat tibial fractures. The data reported here demonstrate the potential for using calcium glycinate as an agent compensating for bone tissue calcium deficiency. |
| doi_str_mv | 10.1007/s11094-013-0914-5 |
| format | Article |
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2
was synthesized and the chemical composition and structure of this chelate were studied. The possibility of using this calcium glycinate complex as a regulator of bone tissue metabolism was studied in development of experimental osteoporosis in mice and during healing of rat tibial fractures. The data reported here demonstrate the potential for using calcium glycinate as an agent compensating for bone tissue calcium deficiency.</description><subject>Alfacalcidol</subject><subject>Calcifediol</subject><subject>Fractures</subject><subject>Glycine</subject><subject>Medicine</subject><subject>Organic Chemistry</subject><subject>Osteoporosis</subject><subject>Pharmacology/Toxicology</subject><subject>Pharmacy</subject><subject>Physiological aspects</subject><subject>Vitamin D</subject><issn>0091-150X</issn><issn>1573-9031</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNp9kd1KAzEQhYMoWKsP4F3A662ZJtmfy7bUWmgp-APehWw2aVN2s5JsL_oAvrdp1xtBJIGBM-cbZjgI3QMZASHZYwAgBUsI0IQUwBJ-gQbAM5oUhMIlGpCoJsDJxzW6CWFPSKToeIC-Xo-u2-lgA24Nnsla2UODF_VRWSc7jaWrcOzjuTFadWfTMpaNlzWeVI11NnRedrZ1OP6pbdVON1bF7lrLcPD6jExbp6PQybKtbWiwdXhtVT_9RXbhFl0ZWQd991OH6P1p_jZ7TlabxXI2WSWKct4lVcmoygpp8qLSeT7mKSWc5awACSwtWZnnkpRjVWSScyIrYGWqQIM2GU-1zukQPfRzt7LWwjrTxuVVY4MSE8o4yWiaQnSN_nDFV51Oi6cYG_VfAPSA8m0IXhvx6W0j_VEAEad4RB-PiPGIUzyCR2bcMyF63VZ7sW8P3sXr_4G-AcmNkec</recordid><startdate>20130601</startdate><enddate>20130601</enddate><creator>Luneva, S. N.</creator><creator>Nakoskin, A. N.</creator><creator>Vaganova, L. A.</creator><general>Springer US</general><general>Springer</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20130601</creationdate><title>Synthesis of Calcium Glycinate and the Effects of Its Oral Administration on Biochemical Measures of Bone Metabolism in Mice and Rats</title><author>Luneva, S. N. ; Nakoskin, A. N. ; Vaganova, L. A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c355t-db43c79af89de8825630548491a146b4b88a0b2c97a550ad14b6c1e1ef756ee83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Alfacalcidol</topic><topic>Calcifediol</topic><topic>Fractures</topic><topic>Glycine</topic><topic>Medicine</topic><topic>Organic Chemistry</topic><topic>Osteoporosis</topic><topic>Pharmacology/Toxicology</topic><topic>Pharmacy</topic><topic>Physiological aspects</topic><topic>Vitamin D</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Luneva, S. N.</creatorcontrib><creatorcontrib>Nakoskin, A. N.</creatorcontrib><creatorcontrib>Vaganova, L. A.</creatorcontrib><collection>CrossRef</collection><jtitle>Pharmaceutical chemistry journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Luneva, S. N.</au><au>Nakoskin, A. N.</au><au>Vaganova, L. A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Synthesis of Calcium Glycinate and the Effects of Its Oral Administration on Biochemical Measures of Bone Metabolism in Mice and Rats</atitle><jtitle>Pharmaceutical chemistry journal</jtitle><stitle>Pharm Chem J</stitle><date>2013-06-01</date><risdate>2013</risdate><volume>47</volume><issue>3</issue><spage>146</spage><epage>150</epage><pages>146-150</pages><issn>0091-150X</issn><eissn>1573-9031</eissn><abstract>The complex Ca(Gly)
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was synthesized and the chemical composition and structure of this chelate were studied. The possibility of using this calcium glycinate complex as a regulator of bone tissue metabolism was studied in development of experimental osteoporosis in mice and during healing of rat tibial fractures. The data reported here demonstrate the potential for using calcium glycinate as an agent compensating for bone tissue calcium deficiency.</abstract><cop>Boston</cop><pub>Springer US</pub><doi>10.1007/s11094-013-0914-5</doi><tpages>5</tpages></addata></record> |
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| ispartof | Pharmaceutical chemistry journal, 2013-06, Vol.47 (3), p.146-150 |
| issn | 0091-150X 1573-9031 |
| language | eng |
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| subjects | Alfacalcidol Calcifediol Fractures Glycine Medicine Organic Chemistry Osteoporosis Pharmacology/Toxicology Pharmacy Physiological aspects Vitamin D |
| title | Synthesis of Calcium Glycinate and the Effects of Its Oral Administration on Biochemical Measures of Bone Metabolism in Mice and Rats |
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