The effect of a combination of β D-Glucan and Propionibacterium granulosum on productive performance and immune modulation of immunocompromised and non-immunocompromised broiler chickens

Aim: The effect of a specific combination of a soluble β (1-3) D-Glucan and Propionibacterium granulosum (Betamune®) was investigated on productive performance, immune response and immune dysfunction caused by cyclophosphamide (CP) in broiler chickens. Materials and Methods: Three hundred and sixty one-day-old broiler chicks were randomly allocated into four groups for 5 weeks. Betamune® supplementation of 0.25 ml / L drinking water (presence or absence) for the first 7 days of age and CP (presence or absence) subcutaneous inoculation with 4 mg / chick for the first 3 days of life was done. Results: Treatment of broiler chicks with Betamune® improved productive performance variables as compared with the blank control birds, where there were 10 points less in cumulative feed conversion ratio and significant increase (P