Synthesis and anticoagulant activity of [alpha]-oxocarboxylic acid derivatives
Water-soluble compounds were prepared by the reaction of [alpha]-oxocarboxylic acids with heterocyclic amines and the reaction of 2-(2-hydroxyphenyl)-2-oxoethanoic acid with sodium carbonate. Their effects on the blood coagulation system were studied. Compounds with high anticoagulant activity were...
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| Veröffentlicht in: | Pharmaceutical chemistry journal 2013-03, Vol.46 (12), p.711 |
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| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | Water-soluble compounds were prepared by the reaction of [alpha]-oxocarboxylic acids with heterocyclic amines and the reaction of 2-(2-hydroxyphenyl)-2-oxoethanoic acid with sodium carbonate. Their effects on the blood coagulation system were studied. Compounds with high anticoagulant activity were identified. Keywords: [alpha]-oxocarboxylic acids, anticoagulant activity |
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| ISSN: | 0091-150X |