Monoclonal gammopathy of undetermined significance multiple myeloma: IMWG consensus perspectives risk factors for progression and guidelines for monitoring and management

Monoclonal gammopathy of undetermined significance multiple myeloma: IMWG consensus perspectives risk factors for progression and guidelines for monitoring and management

Monoclonal gammopathy of undetermined significance (MGUS) was identified in 3.2% of 21 463 residents of Olmsted County, Minnesota, 50 years of age or older. The risk of progression to multiple myeloma, Waldenstrom's macroglobulinemia, AL amyloidosis or a lymphoproliferative disorder is approxim...

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Veröffentlicht in:Leukemia 2010-06, Vol.24 (6), p.1121
Hauptverfasser: Kyle, R.A, Durie, B.G.M, Rajkumar, S.V, Landgren, O, Blade, J, Merlini, G, Kroger, N, Einsele, H, Vesole, D.H, Dimopoulos, M, San Miguel, J, Avet-Loiseau, H, Hajek, R, Chen, W.M, Anderson, K.C, Ludwig, H, Sonneveld, P, Pavlovsky, S, Palumbo, A, Richardson, P.G, Barlogie, B, Greipp, P, Vescio, R, Turesson, I, Westin, J, Boccadoro, M
Format: Artikel
Sprache:eng
Schlagworte:
Care and treatment
Distribution
Monoclonal gammopathies
Multiple myeloma
Practice guidelines (Medicine)
Risk factors
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Zusammenfassung:Monoclonal gammopathy of undetermined significance (MGUS) was identified in 3.2% of 21 463 residents of Olmsted County, Minnesota, 50 years of age or older. The risk of progression to multiple myeloma, Waldenstrom's macroglobulinemia, AL amyloidosis or a lymphoproliferative disorder is approximately 1% per year. Low-risk MGUS is characterized by having an M protein
ISSN:0887-6924
DOI:10.1038/leu.2010.60