Pleural effusion due to the ovarian hyperstimulation syndrome/Over hiperstimulasyon sendromuna bagli plevral efuzyon

Over stimulasyonu, folikuler gelisim ve olgunlasmayi artiran ve Ovulation induction is a treatment that aimed to increase the pregnancy probability by increasing the follicular growth and maturation. The most frequent complication is ovarian hyperstimulation syndrome (OHSS). Pleural effusion and abdominal ascites accumulation frequently accompany this syndrome. A 28 year old nulligravida with a 7 year history of infertility presented with a dry cough and left pleuritic chest pain. 1 week before admission dyspnea had developed and chest x-ray demonstrated a moderate left pleural effusion. Plasma estradiol and β-HCG concentrations were 4001pg/ml and 183 IU/L respevtively. Pelvic ultrasonography showed bilateral enlarged ovaries with numerous follicular cysts and ascites compatible with ovarian hyperstimulation syndrome (OHSS). In the differential diagnosis of pleural effusion in young female patients, the accumulation of pleural effusion due to the recent ovulation induction history should be kept in mind, being especially important in the differential diagnosis of pulmonary embolism. (Tur Toraks Der 2009;11:144-6) Key words: Pleural effusion, ovarian hyperstimulation syndrome, treatment Over stimulasyonu ,folikuler gelisim ve olgunlasmayi artiran ve dolayisiyla gebelik oranini arttirmayi hedefleyen bir yontemdir. En sik gorulen komplikasyonu over hiperstimulasyon sendromu (OHSS)'dur. Plevra sivisi ve intraabdominal sivi bu tabloya eslik edebilir. Yedi yildir infertilite hikayesi olan 28 yasinda nullipar bayan hasta, oksuruk, dispne ve sol plevral agri ile basvurdu. Basvurudan 1 hafta once dispne sikayeti gelisti ve akciger grafisinde orta buyuklukte sol plevral efuzyon saptandi. Plazma estradiol ve β-HCG degerleri sirasiyla 4001pg/ml ve 183IU/L olarak bulundu. Pelvis ultrasonografisinde over hiperstimulasyon sendromu (OHSS) ile uyumlu cok sayida follikuler kist iceren bilateral buyumus overler ve asit belirlendi. Genc kadin olgularda; plevra sivisinin ayirici tanisinda, yakin zamanda over stimulasyonu oykusu alinirsa bu duruma bagli olarak plevra sivisinin gelisebilecegini, bunun da ozellikle tromboemboli ayiriminda onemli olabilecegini vurgulamayi ve OHSS'na bagli plevra sivisini literaturle tekrar gozden gecirmeyi amacladik. (Tur Toraks Der 2009;11:144-6) Anahtar sozcukler: Plevral efuzyon, over hiperstimulasyon sendromu, tedavi