Synergistic hepatoprotective effect of Schisandrae lignans with Astragalus polysaccharides on chronic liver injury in rats

The aim of this study was to investigate the synergistic hepatoprotective effect of lignans from Fructus Schisandrae chinensis (LFS) with Astragalus polysaccharides (APS) on chronic liver injury in male Sprague-Dawley rats. Subcutaneous injection of 10% CCl 4 twice a week for 3 months resulted in si...

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Veröffentlicht in:	Phytomedicine (Stuttgart) 2009-09, Vol.16 (9), p.805-813
Hauptverfasser:	Yan, Fei, Zhang, Qiao-Yan, Jiao, Lei, Han, Ting, Zhang, Hong, Qin, Lu-Ping, Khalid, Rahman
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Astragalus (Plants) Astragalus membranaceus Astragalus polysaccharides Carbon Tetrachloride Care and treatment Chemical and Drug Induced Liver Injury - drug therapy Chemical and Drug Induced Liver Injury - enzymology Chemical and Drug Induced Liver Injury - pathology Chemical properties Chronic Disease Drug Synergism Drug Therapy, Combination Enzymes - blood Fatty Liver - prevention & control Fructus Schisandrae chinensis Fruit Health aspects Hepatoprotective Lignans - pharmacology Lignans - therapeutic use Liver - drug effects Liver - enzymology Liver - pathology Liver diseases Male Malondialdehyde - blood Phytotherapy Plant Extracts - pharmacology Plant Extracts - therapeutic use Plant Roots Polysaccharides - pharmacology Polysaccharides - therapeutic use Protective Agents - pharmacology Protective Agents - therapeutic use Rats Rats, Sprague-Dawley Rattus Schisandra Synergistic
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Beschreibung
Zusammenfassung:	The aim of this study was to investigate the synergistic hepatoprotective effect of lignans from Fructus Schisandrae chinensis (LFS) with Astragalus polysaccharides (APS) on chronic liver injury in male Sprague-Dawley rats. Subcutaneous injection of 10% CCl 4 twice a week for 3 months resulted in significantly ( p
ISSN:	0944-7113 1618-095X
DOI:	10.1016/j.phymed.2009.02.004