Purification strategies to process 5 g/L titers of monoclonal antibodies: altering the order of operations, using new resins, and increasing dynamic binding capacity can obviate the need for major facilty changes

Purification strategies to process 5 g/L titers of monoclonal antibodies: altering the order of operations, using new resins, and increasing dynamic binding capacity can obviate the need for major facilty changes

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Veröffentlicht in:Biopharm international 2009-03, Vol.22 (3), p.S8
Hauptverfasser: Trexler-Schmidt, Melody, Sze-Khoo, Stefanie, Cothran, Amber R, Thai, Binh Q, Sargis, Sandy, Lebreton, Benedicte, Kelley, Brian, Blank, Gregory S
Format: Magazinearticle
Sprache:eng
Schlagworte:
Armored vehicles
Biological products industry
Bookbinding
Capacity
Chemical plants
Immunoglobulins
Integrated logistic support
Ion exchange resins
Monoclonal antibodies
Phosphoric acid
Production management
Protein binding
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ISSN:1542-166X