Cadmium chloride-catalyzed regioselective opening of oxiranes with aromatic amines An improved protocol for the synthesis of 2-amino alcohols

Epoxides undergo rapid CdCl 2 -catalyzed ring-opening reaction with aromatic amines in mild reaction conditions (room temperature), affording the corresponding 2-amino alcohols with high regioselectivity.Key words: epoxides, aromatic amines, cadmium chloride, 2-amino alcohols.

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Veröffentlicht in:Canadian journal of chemistry 2007-01, Vol.85 (1), p.37-41
Hauptverfasser: Kumar, S Ramesh, Leelavathi, P
Format: Artikel
Sprache:eng
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Zusammenfassung:Epoxides undergo rapid CdCl 2 -catalyzed ring-opening reaction with aromatic amines in mild reaction conditions (room temperature), affording the corresponding 2-amino alcohols with high regioselectivity.Key words: epoxides, aromatic amines, cadmium chloride, 2-amino alcohols.
ISSN:0008-4042
1480-3291
DOI:10.1139/v06-186