Evaluation of insulin resistance in individuals with severe obesity candidates for bariatric surgery/AVALIACAO DA RESISTENCIA INSULINICA EM INDIVIDUOS COM OBESIDADE GRAVE CANDIDATOS A CIRURGIA BARIATRICA

Severe obesity is a disease that has reached worldwide proportions, and consequent increase in surgical treatment. This, besides reducing body fat, also helps to reduce associated comorbidities, such as insulin resistance (IR) and diabetes. The aim of this study was to evaluate IR in obese individuals in the preoperative period of bariatric surgery. A cross-sectional study was carried out with patients admitted for bariatric surgery at Hospital Universitario Oswaldo Cruz (HUOC-UPE) in Recife-PE. Insulin resistance was assessed by triglyceride-glucose index (TyG index) and Triglyceride/HDL-c ratio (TG/HDL). Body composition was obtained by dual X-ray emission densitometry (DEXA). Sociodemographic data, anthropometric and biochemical variables, physical activity level, and alcohol intake were also collected. Sixty patients participated, with a mean age of 38.88 [+ or -] 9.67 years, the majority being female, with an education level of more than 10 years, classified as active and at low risk for alcohol dependence. Men presented significantly higher values for weight, neck circumference, waist circumference and lean body mass (Kg). The candidates had IR, by TyG index and TG/HDL ratio, with females showing higher TyG index (p=0.037). Therefore, evaluating insulin resistance by easily accessible parameters in the preoperative period allows the adoption of early intervention strategies and thus reduce the consequences from its non-treatment. Key words: Morbid obesity, Bariatric surgery, Insulin resistance A obesidade grave e uma doenca que vem atingindo proporcoes mundiais, e consequente aumento do tratamento cirurgico. Este, alem da reducao da gordura corporal, tambem auxilia na reducao das comorbidades associadas, como resistencia insulinica (RI) e diabetes. O objetivo do estudo foi avaliar RI em individuos obesos no pre-operatorio de cirurgia bariatrica. Foi realizado um estudo transversal, com pacientes internados para realizacao de cirurgia bariatrica, no Hospital Universitario Oswaldo Cruz (HUOC-UPE) de Recife-PE. A resistencia insulinica foi avaliada pelos indice triglicerideo-glicose (indice TyG) e a razao triglicerideo/HDL-c (TG/HDL). A composicao corporal foi obtida pela densitometria por dupla emissao de raios-X (DEXA). Dados sociodemograficos, variaveis antropometricas, bioquimicas, nivel de atividade fisica e ingestao de alcool tambem foram coletados. Participaram 60 pacientes, com media de idade de 38,88 [+ or -] 9,67 anos, sendo maioria do sexo fe