Synthesis and Structure of Methyl 6-Aryl-5-aroyl-4-hydroxy2-oxohexahydropyrimidine-4-carboxylates

Synthesis and Structure of Methyl 6-Aryl-5-aroyl-4-hydroxy2-oxohexahydropyrimidine-4-carboxylates

The reaction of aroylpyruvic acids methyl esters with aromatic aldehyde and urea (thiourea) in methanol leads to the formation of methyl 6-aryl-5-aroyl-4-hydroxy-2-oxo(thioxo)hexahydropyrimidine-4-carboxylates. Structure of the obtained compounds was established by .sup.1H, .sup.13C NMR spectroscopy...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Russian journal of general chemistry 2022-10, Vol.92 (10), p.1894
Hauptverfasser: Gein, V. L, Zamaraeva, T. M, Gorgopina, E. V, Dmitriev, M.V
Format: Artikel
Sprache:eng
Schlagworte:
Nuclear magnetic resonance spectroscopy
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The reaction of aroylpyruvic acids methyl esters with aromatic aldehyde and urea (thiourea) in methanol leads to the formation of methyl 6-aryl-5-aroyl-4-hydroxy-2-oxo(thioxo)hexahydropyrimidine-4-carboxylates. Structure of the obtained compounds was established by .sup.1H, .sup.13C NMR spectroscopy and single crystal X-ray diffraction analysis.
ISSN:1070-3632
DOI:10.1134/S1070363222100036