Bioequivalence of RU-31 Tablet Dosage Form

The bioequivalence of the tablet dosage form of RU-31 substance was studied. The main pharmacokinetic parameters were determined. The actual relative bioequivalence index was calculated and turned out to be ~100%. RU-31 from tablets did not accumulate upon triple administration at a dose of 10 mg/kg...

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Veröffentlicht in:Pharmaceutical chemistry journal 2021-07, Vol.55 (4), p.328-330
Hauptverfasser: Spasov, A. A., Smirnova, L. A., Ryabukha, A. F., Kuznetsov, K. A., Velikopol’skaya, M. V., Yakovlev, D. S.
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container_title Pharmaceutical chemistry journal
container_volume 55
creator Spasov, A. A.
Smirnova, L. A.
Ryabukha, A. F.
Kuznetsov, K. A.
Velikopol’skaya, M. V.
Yakovlev, D. S.
description The bioequivalence of the tablet dosage form of RU-31 substance was studied. The main pharmacokinetic parameters were determined. The actual relative bioequivalence index was calculated and turned out to be ~100%. RU-31 from tablets did not accumulate upon triple administration at a dose of 10 mg/kg.
doi_str_mv 10.1007/s11094-021-02421-0
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subjects Medicine
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
title Bioequivalence of RU-31 Tablet Dosage Form
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