Bioequivalence of RU-31 Tablet Dosage Form

Bioequivalence of RU-31 Tablet Dosage Form

The bioequivalence of the tablet dosage form of RU-31 substance was studied. The main pharmacokinetic parameters were determined. The actual relative bioequivalence index was calculated and turned out to be ~100%. RU-31 from tablets did not accumulate upon triple administration at a dose of 10 mg/kg...

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Veröffentlicht in:Pharmaceutical chemistry journal 2021-07, Vol.55 (4), p.328-330
Hauptverfasser: Spasov, A. A., Smirnova, L. A., Ryabukha, A. F., Kuznetsov, K. A., Velikopol’skaya, M. V., Yakovlev, D. S.
Format: Artikel
Sprache:eng
Schlagworte:
Medicine
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
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Zusammenfassung:The bioequivalence of the tablet dosage form of RU-31 substance was studied. The main pharmacokinetic parameters were determined. The actual relative bioequivalence index was calculated and turned out to be ~100%. RU-31 from tablets did not accumulate upon triple administration at a dose of 10 mg/kg.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-021-02421-0