Aggressive Surgical Resection of Enormous Cervical Metastasis from Nasopharyngeal Carcinoma/Agresivni kirurski zahvat vadenja velike vratne metastaze iz nazofaringealnog karcinoma

While nasopharyngeal carcinoma (NPC) commonly presents lymphoid metastases, the enormous cervical metastasis causing dysphagia and limitation of neck motion is not a familiar symptom for most of NPC cases. We report a 23-year-old male with undifferentiated carcinoma of the nasopharynx, stage (T3N2MO), who had undergone aggressive surgical resection of bilateral huge cervical mass first followed by concurrent chemo-radiotherapy with cisplatin-based regimens. The postoperative clinical course was uneventful and follow-up, 2 years later, revealed no recurrence of primary lesion and neck metastases. We recommend that aggressive surgical resection may be considered when NPC patients significantly suffer clinical symptoms from a huge cervical metastasis. Key words Nasopharyngeal Carcinoma; Cervical Metastasis; Resection Doknazofaringealni karcinom (NPK) obicno prate limfoidne metastaze, golema cervikalna metastaza koja uzrokuje disfagiju i ogranicava pokrete vrata nije uobicajen simptom za vecinu slucajeva NPK-a. Opisan je slucaj 23-godisnjeg muskarca s nediferenciranim rakom nazofarinksa stupnja T3N2MO, koji je prvi put bio podvrgnut agresivnoj kirurskoj bilateralnoj resekciji velike mase u vratu, nakon cega je slijedila istodobna kemo- i radioterapija s terapijama na temelju cisplatina. Postoperativni klinicki tijek bio je bez osobitosti, a na kontroli dvije godine poslije nije otkrivena ponovna pojava ni primarne lezije, ni metastaze u vratu. Ako bolesnici s NPK-om pate od klinickih simptoma zbogvelikih metastaza u vratu, preporucujemo da se u obzir uzme agresivna kirurska resekcija. Kljucne rijeci nazofaringealni karcinom, metastaze u vratu, resekcija