Bioequivalence of a Dosage form of the New Drug Mefebut
The bioequivalence of mefebut drug substance and its tablet dosage form was investigated by studying the main pharmacokinetic parameters and calculating the relative bioavailability. The results showed that mefebut circulated for up to 4 h in rabbit blood after peroral administration. The relative b...
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| Veröffentlicht in: | Pharmaceutical chemistry journal 2018-09, Vol.52 (6), p.495-496 |
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| container_end_page | 496 |
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| container_issue | 6 |
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| container_title | Pharmaceutical chemistry journal |
| container_volume | 52 |
| creator | Smirnova, L. A. Suchkov, E. A. Ryabukha, A. F. Kuznetsov, K. A. Velikopol’skaya, M. V. Tyurenkov, I. N. Bakulin, D. A. Stepanova, É. F. Shevchenko, A. M. |
| description | The bioequivalence of mefebut drug substance and its tablet dosage form was investigated by studying the main pharmacokinetic parameters and calculating the relative bioavailability. The results showed that mefebut circulated for up to 4 h in rabbit blood after peroral administration. The relative bioavailability was 97.4%. |
| doi_str_mv | 10.1007/s11094-018-1846-x |
| format | Article |
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| subjects | Medicine Organic Chemistry Pharmacology/Toxicology Pharmacy |
| title | Bioequivalence of a Dosage form of the New Drug Mefebut |
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