Analgesic and anti-inflammatory effects of Arnica montana 12CH in comparison with ketoprofen in dogs/Analgesia e acao antiinflamatoria da Arnica montana 12CH comparativamente ao cetoprofeno em caes

This study aimed to evaluate the analgesic and anti-inflammatory effects of Arnica montana 12CH comparatively to ketoprofen in dogs undergoing ovariohysterectomy. Sixteen female dogs were randomly distributed in two groups of eight animals and received 1 mg [kg.sup.-1] of ketoprofen (TC) and 5 globules of Arnica Montana 12CH (TA) by oral route. After 60 minutes, the dogs were sedated with acepromazine (0.05mg [kg.sup.-1], IV), followed by anesthetic induction with propofol (5mg [kg.sup.-1] IV) and maintained with isoflurane. Heart rate, respiratory rate, systolic blood pressure, arterial blood gases, serum cortisol concentration and degree of analgesia and inflammation were measured. Additional morphine (0.5mg [kg.sup.-1]IM) was given when the analgesia was insufficient. Statistical analyses were performed by ANOVA and Tukey tests (P