Direct synthesis of ESBO derivatives-[sup.18]O labelled with dioxirane

This work addresses a new approach developed in our laboratory, consisting in the application of isolated dimethyldioxirane (DDO, 1a) labelled with [sup.18] for synthesis of epoxidized glyceryl linoleate (Gly-LLL, 2). We expect that this work could contribute in improving analytical methods for the determination of epoxidized soybean oil (ESBO) in complex food matrices by adopting an [sup.18] O-labelled-epoxidized triacylglycerol as an internal standard.