Synthesis of 2, 5-dihydroisothiazole derivatives. [2.sup.]. 3-aryl-substituted 2-alkyl-5-arylimino-2, 5-dihydroisothiazoles

Synthesis of 2, 5-dihydroisothiazole derivatives. [2.sup.]. 3-aryl-substituted 2-alkyl-5-arylimino-2, 5-dihydroisothiazoles

A series of new 2-alkyl-5-arylimino-2, 5-dihydroisothiazoles, substituted at position 3 with aryl and hetaryl groups and not substituted at position 4 was prepared by oxidative cyclization of N-arylamides of 3-alkylaminoprop-2-enethioic acids. The formation of the starting thioanilides was investiga...

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Veröffentlicht in:Chemistry of heterocyclic compounds (New York, N.Y. 1965) N.Y. 1965), 2014-04, Vol.50 (1), p.87
Hauptverfasser: Skrastina, I, Baran, A, Muceniece, D, Popelis, J
Format: Artikel
Sprache:eng
Schlagworte:
Pyridine
Schiff bases
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Zusammenfassung:A series of new 2-alkyl-5-arylimino-2, 5-dihydroisothiazoles, substituted at position 3 with aryl and hetaryl groups and not substituted at position 4 was prepared by oxidative cyclization of N-arylamides of 3-alkylaminoprop-2-enethioic acids. The formation of the starting thioanilides was investigated by reacting the respective N-alkylimines of acetophenones with isothiocyanates. The main by-products were identified and characterized. Keywords: 2-alkyl-3-aryl(hetaryl)-5-arylimino-2, 5-dihydroisothiazole, N-arylamides of 3-alkylamino 3-aryl(hetaryl)prop-2-enethioic acid, oxidative cyclization.
ISSN:0009-3122