Quantitative HPLC determination of cynaropicrin in Centaurea Scabiosa dry extract

Quantitative HPLC determination of cynaropicrin in Centaurea Scabiosa dry extract

An HPLC method for quantitative determination of cynaropicrin in Centaurea scabiosa L. dry extract obtained using 40% aqueous ethanol has been developed and its performance has been validated. The proposed method is specific; ensures high accuracy, reproducibility, and linearity in an analytical ran...

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Veröffentlicht in:Pharmaceutical chemistry journal 2011-12, Vol.45 (9), p.560-563
Hauptverfasser: Kaminskii, I. P., Krasnov, E. A., Kadyrova, T. V., Ivasenko, S. A., Rakhimova, B. B., Adekenov, S. M.
Format: Artikel
Sprache:eng
Schlagworte:
Chromatography
Medicine
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
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Zusammenfassung:An HPLC method for quantitative determination of cynaropicrin in Centaurea scabiosa L. dry extract obtained using 40% aqueous ethanol has been developed and its performance has been validated. The proposed method is specific; ensures high accuracy, reproducibility, and linearity in an analytical range of ±30%; and can be used for reliable quality control of C. scabiosa L. dry extract and related preparations.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-011-0679-7