DART mass spectrometry: rapid analysis of soft medicinal formulations

DART mass spectrometry: rapid analysis of soft medicinal formulations

The possibility of using the DART mass spectrometry method for rapid analysis of soft medicinal formulations is considered. Studies of “tetracycline”, “Sintomycin Liniment”, and “Levomecol” creams and suppositories based on hard fat were studied. The possibility of using this method for the rapid sc...

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Veröffentlicht in:Pharmaceutical chemistry journal 2012-02, Vol.45 (11), p.698-700
Hauptverfasser: Chernetsova, E. S., Abramovich, R. A., Revel’skii, I. A.
Format: Artikel
Sprache:eng
Schlagworte:
Mass spectrometry
Medicine
Methods of Analysis and Process Control
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
Structure of Chemical Compounds
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Zusammenfassung:The possibility of using the DART mass spectrometry method for rapid analysis of soft medicinal formulations is considered. Studies of “tetracycline”, “Sintomycin Liniment”, and “Levomecol” creams and suppositories based on hard fat were studied. The possibility of using this method for the rapid screening of medicinal formulations in search of counterfeits is discussed. This is the first report of the analysis of suppositories using DART mass spectrometry.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-012-0705-4