Advanced Materials: three-dimensional biomimetic patterning in hydrogels to guide cellular organisation

The three-dimensional biomimetic patterning via confocal imaging and two-photon laser scanning lithography of photocrosslinkable acrylate-terminated poly(ethylene glycol)(PEG) hydrogels rendered biodegradable by incorporation of a matrix metalloproteinase-sensitive peptide and permeated with fluores...

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Veröffentlicht in:	Cellular polymers 2012-09, Vol.31 (5), p.275
Hauptverfasser:	Culver, J.C, Hoffmann, J.C, Poche, R.A, Slater, J.H, West, J.L, Dickinson, M.E
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomimetics Chemical properties Colloids Composition Identification and classification Imaging systems Methods Polyethylene glycol
Online-Zugang:	Volltext
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Zusammenfassung:	The three-dimensional biomimetic patterning via confocal imaging and two-photon laser scanning lithography of photocrosslinkable acrylate-terminated poly(ethylene glycol)(PEG) hydrogels rendered biodegradable by incorporation of a matrix metalloproteinase-sensitive peptide and permeated with fluorescently labelled acrylate-PEG-Arg-Gly-Asp-Ser is described. The organisation of cells into a network matching the original image in the presence of the patterned hydrogels was investigated and the results are discussed in terms of potential applications. 17 refs.
ISSN:	0262-4893