Histopathological studies on the effects of the ethanolic extract of the fruits of Garcinia kola on selected organs of the dog/ Estudio histopatologico del efecto de los extractos etanolicos de los frutos de Garcinia kola en organos seleccionados de perro

The ethanolic extract of Garcinia kola was administered to dogs to investigate the possible effects on selected organs of the dog. Two doses of the extract (500mg/Kg and 1000mg/Kg) were daily administered to the test animals for a period of 6 weeks. A dose related response was observed in the severi...

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Veröffentlicht in:International journal of morphology 2008-12, Vol.26 (4), p.1069
Hauptverfasser: Nottidge, H.O, Omobowale, T.O, Taiwo, V.O, Omotoso, M.A
Format: Artikel
Sprache:spa
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Zusammenfassung:The ethanolic extract of Garcinia kola was administered to dogs to investigate the possible effects on selected organs of the dog. Two doses of the extract (500mg/Kg and 1000mg/Kg) were daily administered to the test animals for a period of 6 weeks. A dose related response was observed in the severity of histopathological changes observed in the testes, liver, kidney and small intestine of animals in the test groups. Despite the reported potentially beneficial effects of Garcinia kola, its use as a medicinal plant should be with great caution. KEY WORDS: Garcinia kola; Dog; Histopathological effects. Fue administrado a perros extracto etanolico de Garcinia kola, para investigar los posibles efectos sobre determinados organos. Dos dosis del extracto (500mg/Kg y 1000mg/Kg) fueron administradas diariamente a los animales durante un periodo de 6 semanas. Se observo una relacion de la dosis con la gravedad en la respuesta de los cambios histopatologicos observados en testiculos, higado, rinon e intestino delgado de los animales. A pesar de los informes sobre efectos potencialmente beneficiosos de Garcinia kola, su uso como planta medicinal debe ser con mucha precaucion. PALABRAS CLAVE: Garcinia kola; Perro; Efectos histopatologicos.
ISSN:0717-9367