"Reports of My Death Were Greatly Exaggerated": Behavior Genetics in the Postgenomic Era

Behavior genetics studies how genetic differences among people contribute to differences in their psychology and behavior. Here, I describe how the conclusions and methods of behavior genetics have evolved in the postgenomic era in which the human genome can be directly measured. First, I revisit th...

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Veröffentlicht in:Annual review of psychology 2021-01, Vol.72 (1), p.37-60
1. Verfasser: Harden, K. Paige
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description Behavior genetics studies how genetic differences among people contribute to differences in their psychology and behavior. Here, I describe how the conclusions and methods of behavior genetics have evolved in the postgenomic era in which the human genome can be directly measured. First, I revisit the first law of behavioral genetics stating that everything is heritable, and I describe results from large-scale meta-analyses of twin data and new methods for estimating heritability using measured DNA. Second, I describe new methods in statistical genetics, including genome-wide association studies and polygenic score analyses. Third, I describe the next generation of work on gene × environment interaction, with a particular focus on how genetic influences vary across sociopolitical contexts and exogenous environments. Genomic technology has ushered in a golden age of new tools to address enduring questions about how genes and environments combine to create unique human lives.
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source Annual Reviews Complete A-Z List; MEDLINE
subjects Analysis
Behavior
Behavior genetics
Behavioral genetics
Deoxyribonucleic acid
DNA
gene × environment interaction
Gene-Environment Interaction
Genes
Genetic Predisposition to Disease
Genetics
Genetics, Behavioral
Genome-Wide Association Study
Genomes
Genomics
Heritability
Humans
Meta-analysis
Multifactorial Inheritance
polygenic scores
Psychology
Studies
Technology
twin studies
Twin Studies as Topic
title "Reports of My Death Were Greatly Exaggerated": Behavior Genetics in the Postgenomic Era
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