The dynamic changes in cytokine responses in COVID-19: a snapshot of the current state of knowledge

“The role of cytokines in COVID-19” online symposium was presented on 18 June 2020 by the NIH/FDA Immunology and Cytokine Interest Groups and was purposed to discuss our rapidly changing understanding of COVID-19-related cytokine responses in different stages of infection, including the etiologies,...

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Veröffentlicht in:	Nature immunology 2020-10, Vol.21 (10), p.1146-1151
Hauptverfasser:	Buszko, Maja, Park, Jung-Hyun, Verthelyi, Daniela, Sen, Ranjan, Young, Howard A., Rosenberg, Amy S.
Format:	Artikel
Sprache:	eng
Schlagworte:	692/420 692/420/2780 692/699/255/2514 Angioedema - blood Angioedema - immunology Angioedema - pathology Angioedema - virology Angiotensin-Converting Enzyme 2 Anti-Inflammatory Agents - pharmacology Anti-Inflammatory Agents - therapeutic use Antiviral Agents - therapeutic use Betacoronavirus - immunology Biomarkers - blood Biomedical and Life Sciences Biomedicine Clinical Laboratory Techniques - methods Congresses as Topic Coronavirus Infections - blood Coronavirus Infections - diagnosis Coronavirus Infections - drug therapy Coronavirus Infections - epidemiology Coronavirus Infections - immunology Coronaviruses COVID-19 COVID-19 Testing Cytokine Release Syndrome - blood Cytokine Release Syndrome - immunology Cytokine Release Syndrome - virology Cytokines Cytokines - antagonists & inhibitors Cytokines - blood Cytokines - immunology Cytokines - metabolism Genetic aspects Health aspects Humans Immune response Immunology Infectious Diseases Interest groups Internet Kallikrein-Kinin System - drug effects Kallikrein-Kinin System - immunology Life Sciences & Biomedicine Meeting Report Pandemics Peptidyl-Dipeptidase A - metabolism Pneumonia, Viral - blood Pneumonia, Viral - diagnosis Pneumonia, Viral - epidemiology Pneumonia, Viral - immunology Pulmonary Alveoli - immunology Pulmonary Alveoli - pathology SARS-CoV-2 Science & Technology Severity of Illness Index Signal Transduction - drug effects Signal Transduction - immunology Spike Glycoprotein, Coronavirus - immunology Spike Glycoprotein, Coronavirus - metabolism Time Factors Time-to-Treatment
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Beschreibung
Zusammenfassung:	“The role of cytokines in COVID-19” online symposium was presented on 18 June 2020 by the NIH/FDA Immunology and Cytokine Interest Groups and was purposed to discuss our rapidly changing understanding of COVID-19-related cytokine responses in different stages of infection, including the etiologies, downstream consequences and possible mitigation strategies. The recording is available at https://nci.rev.vbrick.com/sharevideo/03106730-66cc-47ba-870b-f6e6274a998a .
ISSN:	1529-2908 1529-2916
DOI:	10.1038/s41590-020-0779-1