The prognostic value of NIRS in preterm infants with

The prognostic value of NIRS in preterm infants with

Late-onset sepsis is frequently seen in preterm infants and is associated with poor neurodevelopmental outcome. White matter damage is proposed as substrate of poor outcome, with contributing factors as regional hypoxia and effects of cytokines on oligodendrocytes. We investigated the relation betwe...

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Veröffentlicht in:PloS one 2019-07, Vol.14 (7)
Hauptverfasser: Zonnenberg, Inge A, Dijk, Jennifer van, Dungen, Frank A. M. van den, Vermeulen, R. Jeroen, Weissenbruch, Mirjam M. van
Format: Artikel
Sprache:eng
Schlagworte:
Analysis
Blood tests
Cytokines
Health aspects
Infant development
Infants
Infection
Near-infrared spectroscopy
Neurodegenerative diseases
Premature infants
Treatment outcome
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Zusammenfassung:Late-onset sepsis is frequently seen in preterm infants and is associated with poor neurodevelopmental outcome. White matter damage is proposed as substrate of poor outcome, with contributing factors as regional hypoxia and effects of cytokines on oligodendrocytes. We investigated the relation between cerebral oxygenation during (suspected) late-onset sepsis and neurodevelopmental outcome. Prospective cohort study, including preterm infants (gestational age
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0220044