Impact of the implementation of new guidelines on the management of patients with HIV infection at an advanced HIV clinic in Kinshasa, Democratic Republic of Congo (DRC)

Impact of the implementation of new guidelines on the management of patients with HIV infection at an advanced HIV clinic in Kinshasa, Democratic Republic of Congo (DRC)

BackgroundHIV continues to be the main determinant morbidity with high mortality rates in Sub-Saharan Africa, with a high number of patients being late presenters with advanced HIV. Clinical management of advanced HIV patients is thus complex and requires strict adherence to updated, empirical and s...

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Veröffentlicht in:BMC infectious diseases 2020-10, Vol.20 (1), p.1-734, Article 734
Hauptverfasser: Mangana, F., Massaquoi, L. D., Moudachirou, R., Harrison, R., Kaluangila, T., Mucinya, G., Ntabugi, N., Van Cutsem, G., Burton, R., Isaakidis, P.
Format: Artikel
Sprache:eng
Schlagworte:
Accuracy
Acquired immune deficiency syndrome
Advanced HIV
AIDS
Algorithms
Analysis
Annual reports
Care and treatment
CD4 antigen
Committees
Diagnosis
Diagnostic systems
Empirical analysis
Guidelines
Health aspects
Health care facilities
Health facilities
HIV
HIV clinical guideline
HIV clinical management
HIV infection
HIV infections
HIV patients
Hospitalization
Hospitals
Human immunodeficiency virus
Infections
Infectious Diseases
Laboratories
Life Sciences & Biomedicine
Management
Morbidity
Mortality
Patients
Physicians
Pneumonia
Practice guidelines (Medicine)
Regression analysis
Regression models
Science & Technology
Sexually transmitted diseases
Statistical analysis
STD
Sub-Saharan Africa
Toxoplasmosis
Tuberculosis
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Zusammenfassung:BackgroundHIV continues to be the main determinant morbidity with high mortality rates in Sub-Saharan Africa, with a high number of patients being late presenters with advanced HIV. Clinical management of advanced HIV patients is thus complex and requires strict adherence to updated, empirical and simplified guidelines. The current study investigated the impact of the implementation of a new clinical guideline on the management of advanced HIV in Kinshasa, Democratic Republic of Congo (DRC).MethodsA retrospective analysis of routine clinical data of advanced HIV patients was conducted for the periods; February 2016 to March 2017, before implementation of new guidelines, and November 2017 to July 2018, after the implementation of new guidelines. Eligible patients were patients with CD4
ISSN:1471-2334
1471-2334
DOI:10.1186/s12879-020-05470-0