Putative Conjugative Plasmids with tcdB and cdtAB Genes in Clostridioides difficile

The major toxins of Clostridioides difficile (TcdA, TcdB, CDT) are chromosomally encoded in nearly all known strains. Following up on previous findings, we identified 5 examples of a family of putative conjugative plasmids with tcdB and cdtAB in clinical C. difficile isolates from multilocus sequenc...

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Veröffentlicht in:Emerging infectious diseases 2020-09, Vol.26 (9), p.2287-2290
Hauptverfasser: Ramírez-Vargas, Gabriel, Rodríguez, César
Format: Artikel
Sprache:eng
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Zusammenfassung:The major toxins of Clostridioides difficile (TcdA, TcdB, CDT) are chromosomally encoded in nearly all known strains. Following up on previous findings, we identified 5 examples of a family of putative conjugative plasmids with tcdB and cdtAB in clinical C. difficile isolates from multilocus sequence typing clades C-I, 2, and 4.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid2609.191447