Linkage Disequilibrium Mapping of the Replicated Type 2 Diabetes Linkage Signal on Chromosome 1q

Linkage Disequilibrium Mapping of the Replicated Type 2 Diabetes Linkage Signal on Chromosome 1q Inga Prokopenko 1 , 2 , Eleftheria Zeggini 1 , 3 , Robert L. Hanson 4 , Braxton D. Mitchell 5 , N. William Rayner 1 , 2 , Pelin Akan 3 , Leslie Baier 4 , Swapan K. Das 6 , 7 , Katherine S. Elliott 1 , Mao Fu 5 , Timothy M. Frayling 8 , Christopher J. Groves 1 , 2 , Rhian Gwilliam 3 , Laura J. Scott 9 , Benjamin F. Voight 10 11 12 13 , Andrew T. Hattersley 8 , Cheng Hu 14 , Andrew D. Morris 15 , Maggie Ng 16 , Colin N.A. Palmer 17 , Marcela Tello-Ruiz 18 , Martine Vaxillaire 19 , Cong-rong Wang 14 , Lincoln Stein 18 20 , Juliana Chan 16 , Weiping Jia 14 , Philippe Froguel 19 21 , Steven C. Elbein 6 , Panos Deloukas 3 , Clifton Bogardus 4 , Alan R. Shuldiner 5 , Mark I. McCarthy 1 , 2 , 22 and for the International Type 2 Diabetes 1q Consortium 1 Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K; 2 Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, U.K.; 3 Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, U.K.; 4 Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona; 5 School of Medicine, University of Maryland, Baltimore, Maryland; 6 Endocrinology Section, Medical Service, Central Arkansas Veterans Healthcare System, Little Rock, Arkansas; 7 Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas; 8 Institute of Clinical and Biomedical Science, Peninsula Medical School, Exeter, U.K.; 9 Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan; 10 Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts; 11 Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts; 12 Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts; 13 Department of Medicine, Harvard Medical School, Boston, Massachusetts; 14 Shanghai Diabetes Institute, Department of Endocrinology & Metabolism, Shanghai Jiaotong University No. 6 People's Hospital, Shanghai, China; 15 Diabetes Research Group, Biomedical Research Institute, University of Dundee, Dundee, U.K.; 16 Department of Medicine and Therapeutics, Chinese University of Hong Kong, Shatin,