Changes Occur in the Central Nervous System of the Nudibranch Berghia verrucicornis (Mollusca, Opisthobranchia) during Metamorphosis

The structure of the larval and juvenile central nervous system (CNS) in Berghia verrucicornis, an aeolid nudibranch, was examined using 1-μm serial sections. The CNS consists of paired optic, cerebral, pleural (also known as sub- and supra-intestinal ganglia), pedal, and buccal ganglia, and a single visceral ganglion. A pleurovisceral loop is present. The organization of the CNS changes as the nudibranch undergoes metamorphosis. In general, there is a condensation of the CNS. The cerebral and pleural ganglia fuse to form the prominent cerebropleural ganglia. The single visceral ganglion fuses with the pleural portion of the left cerebropleural ganglion. The buccal ganglia enlarge and fully organize into a cortex of nerve cell bodies and medulla of nerve fibers. Rhinophoral ganglia develop anterior to each cerebropleural ganglion and a pair of nervous processes extend from each: one to the developing rhinophore and the other anteroventral toward the mouth and associated structures. These metamorphic changes are similar to those seen in other commonly studied opisthobranch species, suggesting that Berghia verrucicornis is an appropriate model for the developmental examination of structure and function in molluscan nervous systems.