The prognostic significance of combined geriatric nutritional risk index and psoas muscle volume in older patients with pancreatic cancer

BackgroundThe geriatric nutritional risk index (GNRI), originally developed as a nutritional assessment tool to evaluate mortality and morbidity in older hospitalized patients (i.e., those aged >= 65years), is regarded as a prognostic factor in several cancers. Body composition is also an importa...

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Veröffentlicht in:BMC cancer 2021-03, Vol.21 (1), p.342-342, Article 342
Hauptverfasser: Sakamoto, Teruhisa, Yagyu, Takuki, Uchinaka, Ei, Miyatani, Kozo, Hanaki, Takehiko, Kihara, Kyoichi, Matsunaga, Tomoyuki, Yamamoto, Manabu, Tokuyasu, Naruo, Honjo, Soichiro, Fujiwara, Yoshiyuki
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Sprache:eng
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Zusammenfassung:BackgroundThe geriatric nutritional risk index (GNRI), originally developed as a nutritional assessment tool to evaluate mortality and morbidity in older hospitalized patients (i.e., those aged >= 65years), is regarded as a prognostic factor in several cancers. Body composition is also an important consideration when predicting the prognosis of patients with cancer. This study aimed to investigate the relationship between the GNRI and psoas muscle volume (PMV) for survival outcomes in patients with pancreatic cancer.MethodsThis retrospective study evaluated the prognostic significance of the GNRI and PMV in 105 consecutive patients aged >= 65years who underwent pancreatectomy for histologically confirmed pancreatic cancer. The patients were divided into high (GNRI >98) and low GNRI groups (GNRI 61.5mm(3)/m(3) for men and 44.1mm(3)/m(3) for women) and low PMV (PMV = 65years with pancreatic cancer.
ISSN:1471-2407
1471-2407
DOI:10.1186/s12885-021-08094-y