ANTIOXIDANT CAPACITY, POLYPHENOL CONTENT AND ANTIPROLIFERATIVE ACTIVITY OF YELLOW, TROPICAL AND ANDEAN BERRIES EXTRACTS OBTAINED FROM MIXTURES OF BLACKBERRY (Rubus glaucus), PASSION FRUIT (Passiflora edulis and Passiflora ligularis), PINEAPPLE (Ananas comosus), GUAVA (Psidium guajava l. Radd) AND PINEAPPLE GUAVA (Acca sellowiana)

Fruits are sources of phytochemicals such as phenols and carotenoids with antioxidant and anticancer activities. The objective of this study was to evaluate the antioxidant and antiproliferative activities of Colombian native fruit extracts (tropical fruit, yellow fruit and Andean berries) that are rich in bioactive compounds and to correlate antioxidant capacity with phenolic content. Antioxidant activity was measured by FRAP and ORAC. Cytotoxic and antiproliferative effects were analyzed using MTT and sulfhorodamine-B respectively on the SW480 cell line. The tropical fruit aqueous extract yielded the highest FRAP and ORAC values and greatest content of total phenolic compounds compared with Andean berries and yellow fruits. Cytotoxic and antiproliferative activities were the lowest in the tropical fruit solution. Correlation analyses for tropical and yellow fruits were similar; both showed positive correlations (p