The synergistic effect of hydroalcoholic extracts of

This study was designed to evaluate the synergistic activities of hydroalcoholic extracts of medicinal plants and and their active components, carvacrol and hypericin against . The synergistic effects of the plants, as well as carvacrol and hypericin, were examined using a checkered method against (...

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Veröffentlicht in:Future science OA 2019-03, Vol.5 (3)
Hauptverfasser: Bahmani, Mahmoud, Taherikalani, Morovat, Khaksarian, Mojtaba, Rafieian-Kopaei, Mahmoud, Ashrafi, Behnam, Nazer, Mohammadreza, Soroush, Setareh, Abbasi, Naser, Rashidipour, Marzieh
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Sprache:eng
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Zusammenfassung:This study was designed to evaluate the synergistic activities of hydroalcoholic extracts of medicinal plants and and their active components, carvacrol and hypericin against . The synergistic effects of the plants, as well as carvacrol and hypericin, were examined using a checkered method against (ATCC 12600). A fractional inhibitory concentration of 0.5 was obtained for combination of and and 0.49 for combination of the active ingredients carvacrol and hypericin, both of which indicated a synergistic effect. This preliminary evaluation demonstrated a synergistic property of and extracts in treating infection. This study indicates that combination of the plants, as well as combination of carvacrol and hypericin, might be used as a new antibacterial strategy against . We studied and evaluated the synergistic activities of hydroalcoholic extracts of oregano and St John's wort and their active components, carvacrol and hypericin, against . The results suggest that a combination of oregano and St John's wort extracts, as well as a combination of hypericin and carvacrol, have potential for use as natural and effective combinations against infections.
ISSN:2056-5623
DOI:10.4155/fsoa-2018-0096