Current diagnostic tools for Sjögren s syndrome

Primary Sjögren s syndrome (pSS) is an autoimmune disease. Eleven classification or diagnostic criteria have been published for pSS since 1965. The American-European Consensus Group criteria have a better specificity than its predecessor; however, they have been criticized. New classification criteria for pSS were proposed by the ACR in 2012. The fact that two different criteria to classify patients with Sjögren s syndrome could be available may introduce some difficulties. New criteria are being discussed by expert groups from the ACR and the European League Against Rheumatism to obtain consensual classification criteria. We describe the objective tests that are useful in practice for a positive diagnosis and assessment of pSS. Furthermore, we present other tests that might be included in future classification criteria.