Propolis: a potential natural product to fight

To evaluate the effect of propolis against species planktonic cells and its counterpart's biofilms. The MIC values, time-kill curves and filamentation form inhibition were determined in planktonic cells. The effect of propolis on biofilms was assessed through quantification of CFUs. MIC values, ranging from 220 to 880 µg/ml, demonstrated higher efficiency on and than on cells. In addition, propolis was able to prevent species biofilm's formation and eradicate their mature biofilms, coupled with a significant reduction on and filamentation. Propolis is an inhibitor of virulence factors and represents an innovative alternative to fight candidiasis.