Plasmodium knowlesi: A Malaria Parasite of Monkeys and Humans

Plasmodium knowlesi is a malaria parasite of monkeys of Southeast Asia that is transmitted by mosquitoes of the Anopheles leucosphyrus group. Humans are frequently infected with this parasite and misdiagnosed as being infected with Plasmodium malariae . The parasite was a major monkey animal model f...

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Veröffentlicht in:	Annual review of entomology 2012-01, Vol.57 (1), p.107-121
1. Verfasser:	Collins, William E
Format:	Artikel
Sprache:	eng
Schlagworte:	animal models Animals Anopheles Anopheles leucosphyrus Biological and medical sciences Borneo Fundamental and applied biological sciences. Psychology genome Haplorhini - parasitology Host-Parasite Interactions human malaria Human protozoal diseases Humans Infectious diseases Insect Vectors - parasitology Insecta Invertebrates Malaria Malaria - immunology Malaria - parasitology Malaria - transmission Mammalia Medical sciences Monkey Diseases - parasitology monkeys mosquitoes parasites Parasitic diseases Plasmodium knowlesi Plasmodium knowlesi - physiology Plasmodium malariae Protozoal diseases Southeast Asia vaccines Vertebrates: general zoology, morphology, phylogeny, systematics, cytogenetics, geographical distribution
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Beschreibung
Zusammenfassung:	Plasmodium knowlesi is a malaria parasite of monkeys of Southeast Asia that is transmitted by mosquitoes of the Anopheles leucosphyrus group. Humans are frequently infected with this parasite and misdiagnosed as being infected with Plasmodium malariae . The parasite was a major monkey animal model for developing antimalarial vaccines and investigations of the biology of parasite invasion. P. knowlesi is the first monkey malaria parasite genome to be sequenced and annotated.
ISSN:	0066-4170 1545-4487
DOI:	10.1146/annurev-ento-121510-133540